Figure 2: Tert reduces mortality and rescues cardiac function after MI. | Nature Communications

Figure 2: Tert reduces mortality and rescues cardiac function after MI.

From: Telomerase expression confers cardioprotection in the adult mouse heart after acute myocardial infarction

Figure 2

(a) Kaplan–Meier survival curves after MI, indicating 17% improved survival after Tert treatment and MI. Statistical analysis was calculated χ2-test. n, number of mice. (b–d) Echocardiography at 1 and 3 weeks in mice injected with AAV9-Tert (blue bars), AAV9-empty (light grey bars) or no virus (dark grey bars) (all three groups suffered MI); or sham-operated mice (red bars) (no virus, no MI) reveals functional improvement in the Tert-treated group. Note, same colours are used throughout the paper. (b) LV end-systolic area, (c) LV end-diastolic area, (d) ejection fraction. n, number of mice; bars show mean values with s.e.m. (error bars). Two-sided Student’s t-test was used for statistical analysis and P-values are shown.

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