Figure 6: Comparative analysis of exon shuffling and exon phase bias.

(a) Comparison of the DCJ distances contributed solely by rearrangements occurring at the subgenic (exon) level in several species pairs. *** indicates significant differences between lancelets and other species pairs (P<1e−16, χ²-test). (b) Comparison of the proportions of internal exon phases 0–0, 1–1 and 2–2 in different species. Only data for exons larger than 100 bp are shown. For all comparisons of 1–1 phased exons between lancelets and other species, P<1e−16 (***; χ²-tests). (c) Comparison of the exon phase biases of non-translocated and translocated domain-containing exons. For all comparisons between non-translocated and translocated 1–1 phased exons in lancelets, P<1e−16 (***; χ²-tests). The error bars show the 95% confidence intervals. More information is provided in Supplementary Note 13.