Figure 4: Structure of the membrane-bound mitoribosome.
From: Organization of the mitochondrial translation machinery studied in situ by cryoelectron tomography
(a) Subtomogram average filtered to 28 Å resolution. The 54S (blue) and 37S (yellow) subunits, the inner mitochondrial membrane (grey) and two distinct contact sites between the mitoribosome and the membrane (C1 and C2) are resolved. Dashed lines indicate the two leaflets of the membrane bilayer. The scale bar corresponds to 5 nm. (b) Atomic model of the 54S subunit (modelled proteins blue, modelled rRNA orange, PDB 1VW3, 1VW4) fitted into the 54S density of the subtomogram average (transparent grey). Some flexible parts of the 54S subunit are not included in the atomic model.
