Figure 4: Structure of the VcFadR–DNA complex. | Nature Communications

Figure 4: Structure of the VcFadR–DNA complex.

From: The 40-residue insertion in Vibrio cholerae FadR facilitates binding of an additional fatty acyl-CoA ligand

Figure 4

(a) The VcFadR dimer bound to DNA. One monomer is slate blue and the other is wheat. (b) Schematic overview of the VcFadR–DNA contacts. Residues that form specific contacts with the DNA are red and those that form nonspecific interactions with the DNA sugar–phosphate are dark blue. The base pairs in the V. cholerae fadB recognition sequence that are different from the E. coli consensus sequence44 are green. Within the consensus sequence, upper and lowercase letters represent nucleotides found more and less frequently, respectively. Residues from chain B are distinguished by a prime following the amino-acid number. (c) View showing a close up of the VcFadR–DNA interface within one monomer. Colours are the same as in b.

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