Table 1 Summary descriptions for the variants associated with HDL-C, LDL-C, TC or TG.

From: Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels

SNP

Chr

Position

EA

NEA

Gene

MAF GoNL

MAF 1-kG

MAFGoNL/MAF1-kG (P value for two population proportions)

rs4752801

11

47,907,641

G

A

Close to the NUP160

0.347

0.338

1.027 (0.258)

rs149580368

17

41,874,745

A

C

Between C17orf105 and MPP3

0.029

0.015

1.923 (<0.0001)

rs77542162

17

67,081,278

G

A

ABCA6

0.030

0.008

3.647 (<0.0001)

rs144984216

19

20,479,901

T

C

ZNF826P

0.028

0.011

2.555 (<0.0001)

rs117162033

19

8,627,569

T

C

MYO1F

0.007

0.007

0.957 (<0.0001)

  1. EA, effect allele; GoNL, Genome of the Netherlands; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MAFGoNL and MAF1 kG, the minor allele frequency of the effect allele in the GoNL reference panel and in the 1-kG reference panel (Phase 1 integrated release v3, April 2012, all ancestries), respectively; NEA, non-effect allele; SNP, single-nucleotide polymorphism; TC, total cholesterol; TG, triglyceride.
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