Figure 5: Downregulation of mTOR–eIF4F does not affect global translation, however, shows decreased level of candidate proteins.
From: Temporal and spatial regulation of translation in the mammalian oocyte via the mTOR–eIF4F pathway
(a,b) 4EGI or Rap treatments during meiotic progression do not affect the overall protein synthesis in the oocytes (data are represented as mean±s.d.; **P<0.01, according to Student’s t-test; n≥3). The overall translation was supressed by puro (puromycin). (c) Translation of TOP motive RL RNA reporter construct is affected in the oocytes with downregulated mTOR–eIF4F pathway (as mean±s.d.; **P<0.01; according to Student’s t-test.
