Figure 8: Enzymatic cutting of trapped DNA.
(a) Illustration of the experiment. (b) A typical current trace showing a single ping followed by two pongs after a pause of tp=5 s. The ECD of the ping is 0.10 pC and those of the pongs are 0.05 and 0.04 pC, sequentially. The wavy lines indicate breaks in the current axis. The current transients near 0.01 and 5.4 s were caused by sudden changes in V. (c) Distributions of pongs per ping–pause–pong cycle, Npong, for three different tp with SmaI present, and for tp=5 s without SmaI. The number of ping–pause–pong cycles performed was 62 with tp=1 s, 93 with tp=5 s, 82 with tp=20 s and 76 with no enzyme present. (d) Distributions of 
(white bars) and 
(grey bars). Both distributions are normalized by the total number of counts, respectively.
