Table 1 The proteins identified in the purified NHEJ complexes using mass spectrometry.
Identified proteins | Flag-IP | ||||||
|---|---|---|---|---|---|---|---|
| Â | Mock | XRCC4 | XLF | PAXX | LIG4 | Ku70 | Ku80 |
DNA-PKcs | 0 | 0.5 | 222.5 | 286.5 | 270 | 212 | 206.5 |
Ku70 | 0 | 1 | 55 | 68 | 71 | 76.5 | 62.5 |
Ku80 | 0 | 0 | 58 | 62.5 | 70 | 73 | 86 |
LIG4 | 0 | 22.5 | 44.5 | 23 | 94 | 0 | 1 |
XRCC4 | 0 | 39 | 57 | 14.5 | 68 | 4 | 1 |
XLF | 0 | 13 | 27 | 0 | 11.5 | 0 | 0 |
PAXX | 0 | 0 | 5.5 | 24 | 8.5 | 9 | 8.5 |
APLF | 0 | 0 | 2.5 | 1.5 | 8 | 1.5 | 1 |
PNKP | 0 | 29 | 0 | 1 | 0 | 0 | 0 |
APTX | 0 | 13 | 0 | 0 | 0 | 0 | 0 |
WRN | 0 | 0 | 0 | 37.5 | 44 | 15.5 | 30 |
