Figure 3: Estimation of crossover interference parameters.
From: Escape from crossover interference increases with maternal age
(a) Fit of three models of interference to the inter-crossover distances observed on chromosome 1, derived from phase-known mothers (red, n=2184) and fathers (blue, n=2092). The interference-free model is shown as a dotted line, the gamma simple interference model is shown as a dashed line and the Housworth–Stahl interference escape model is shown as a solid line. (b) Per-chromosome estimates of the interference parameter as estimated from the Housworth–Stahl interference escape model. Error bars indicate a 95% confidence interval. Note that chr21 in males is excluded due to an extremely high estimate. (c) Per-chromosome estimates of the proportion of events escaping interference. Error bars indicate a 95% confidence interval.
