Figure 3: Locus-specific plot of PA-associated loci reaching genome-wide significance.

Each dot represents the −log10 (P-value) for one genotyped or imputed SNP based on the MQLS test in 2,197 discovery samples of European ancestry. The estimated recombination rates from the 1000 Genomes Project data are shown as blue lines and the genomic locations of genes within the regions of interest are shown at the bottom. SNP colour represents LD with the most significant genotyped SNP (rs9275596). SNP annotations are indicated as follows: triangles, genotyped SNPs; circles, imputed SNPs.