Figure 1: Enrichment of features in regions harbouring SNPs involved in distal SNP–CpG associations.

Outer histograms: number of SNPs involved in distal SNP–CpG associations (light blue), calculated in 7.5 Mb bins; number of piRNA sequences (orange); number of transcription factors (dark blue). Inner links: SNP regions associated with four or more CpG sites. Arrows are pointing from SNPs to the CpG sites they are associated with, and are coloured according to the chromosomes where the SNPs reside.