Figure 4: β3-AR agonism ameliorates dyslipidemia in E3L.CETP mice.
From: Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development
Fasting plasma (a) TG, (c) TC and (d) VLDL-C were measured in WTD-fed E3L.CETP at the indicated time points during treatment with the β3-AR agonist CL316243 or vehicle. The distribution of (b) TG and (e) TC over lipoproteins was determined after 10 weeks of treatment on pooled plasma samples per group. Values are means±s.e.m. (n=13–19 per group or pool). *P<0.05, **P<0.01, ***P<0.001 (unpaired two-tailed Student’s t-test).
