Figure 6: Branching morphogenesis in normal human RPTEC, induced by dimeric macrocycles.
From: Artificial human Met agonists based on macrocycle scaffolds

RPTEC encapsulated in collagen gels were cultured in the presence of 0.42 nM hHGF or 30 nM dimeric macrocycles over 8 days. Arrows indicate tubules formed by RPTEC. Scale bars, 100 μm.