Figure 2: Scope of α,α-disubstituted propanamides.

Reaction conditions: 1 (0.3 mmol), Co(OAc)₂ (0.03 mmol), Ag₂CO₃ (0.75 mmol), PhCO₂Na (0.15 mmol), 0.6 ml PhCl, 150 °C, 24 h. Isolated yield based on three runs of each reaction. ^aRun for 48 h. ^bCo(OAc)₂ (0.06 mmol). Q=8-quinolinyl.