Figure 7: Removal of the quinolyl group.

Reaction conditions: (1) amide (0.15 mmol), BF₃·Et₂O (0.30 mmol), PhI(OAc)₂ (0.45 mmol), MeOH (0.5 ml), 80 °C, 3–8 h; (2) CAN (0.45 mmol), MeCN/H₂O(2.0 ml/0.4 ml), room temperature, 6 h. Isolated yield based on three runs of each reaction. ^aThe methoxylation step was carried out at 50 °C.