Figure 4: Frequency of a canonical Vδ5Dδ2Jδ1 CDR3 sequence in thymus ontogeny and in peripheral tissues. | Nature Communications

Figure 4: Frequency of a canonical Vδ5Dδ2Jδ1 CDR3 sequence in thymus ontogeny and in peripheral tissues.

From: A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6+CD27− subset

Figure 4

Bar graphs show percentages of the canonical CDR3 amino-acid sequence ASGYIGGIRATDKLV among in-frame Vδ5 sequences derived from the indicated fluorescence-activated cell sorting-sorted Vγ4+ T-cell populations. (a) Frequency of the canonical CDR3 sequence in the thymus of day E18 old embryos, 2-week-old pups and 4-month-old adult mice. (b) Frequency of canonical CDR3 sequence in the skin, lung, liver, spleen and pLN. Data represent eight individual samples from one 454-sequencing run.

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