Table 2 Most frequent Vγ4 CDR3 nucleotide sequences that encode the Vγ4 amino-acid sequence SYGLYSSGFHKV.

From: A clonotypic Vγ4Jγ1/Vδ5Dδ2Jδ1 innate γδ T-cell population restricted to the CCR6+CD27 subset

Vγ4 (5′–3′)

N

P

Jγ1 (5′–3′)

Frequency

S Y G Stop..

  

..S S G F H K V

 

tcctacggctaaag

  

atagctcaggttttcacaaggta

Germline

tcctacggc.....

 

tat

atagctcaggttttcacaaggta

61–62%

tcctacggc.....

 

ctat

atagctcaggttttcacaaggta

25–27%

tcctacgg.....

t

ctat

atagctcaggttttcacaaggta

3.8–5%

tcctacgg......

gt

tat

atagctcaggttttcacaaggta

1.5–2.2%

tcctacgg......

 

gctat

atagctcaggttttcacaaggta

0.9–1.2%

tcctacggc.....

ctt

t

atagctcaggttttcacaaggta

0.6–0.7%

  1. The germline sequences of related gene segments are demonstrated in red. N and P refer to N- and P-nucleotides, respectively.