Figure 6: Numerical correlation between dietary or clinical indices and MLGs.
From: Gut microbiome development along the colorectal adenoma–carcinoma sequence
Spearman’s correlation coefficient was calculated between the relative abundance of each MLG (>100 genes) and the level of risk factors or clinical phenotypes indicated. Red, positive correlation; blue, negative correlation. +, P<0.05, FDR=0.4131; *, P<0.01, FDR=0.2635. The name of each MLG was coloured according to its direction of enrichment, that is, green if higher in controls than in carcinomas, red if higher in carcinomas than in controls. Actinomyces viscosus, Alistipes putredinis, Paraprevotella clara, mlg-703, mlg-711, mlg-798, mlg-1602 and mlg-7070 did not have significant correlations with any of the 26 numerical phenotypes (P>0.05, Spearman’s) and are not shown. gamma-glutamyl transferase (GGT), body mass index (BMI), alanine transaminase (ALT), aspartate transaminase (AST), triglyceride (TG), haemoglobin (Hb), low density lipoprotein (LDL), C-reactive protein (CRP), waist–hip ratio (WHR), high density lipoprotein (HDL).
