Figure 2: OR plot and homolog study of rs7739323. | Nature Communications

Figure 2: OR plot and homolog study of rs7739323.

From: Whole-exome sequencing implicates UBE3D in age-related macular degeneration in East Asian populations

Figure 2

(a) The OR plot shows the allelic effects of the T allele of rs7739323 in the discovery stage (216 AMD cases and 1,553 controls) and in the 5 independent cohorts (803 AMD cases and 395 controls of North China, 850 AMD cases and 856 controls of Beijing China, 507 AMD cases and 2,967 controls of Singapore, 981 AMD cases and 757 controls of Japan, 631 AMD cases and 1,967 controls of Hong Kong). P values were generated using logistic regression under the additive model and are presented in parentheses. The error bars represent the 95% confidence intervals (CIs) of the ORs. (b) The homolog study showed that the UBE3D gene is conserved in most animals. However, most animals have a T at this position, whereas only humans and pigs have a C at this position.

Back to article page