Figure 1: Manhattan plots of the first stage GWAS for three myopia-related traits. | Nature Communications

Figure 1: Manhattan plots of the first stage GWAS for three myopia-related traits.

From: Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

Figure 1

Each plot shows −log10-transformed P values for all SNPs. The upper horizontal line represents the genome-wide significance threshold of P<2.82 × 10−8, and the lower line represents the suggestive threshold of P<1.00 × 10−6. Nine SNPs from five genes surpassed the suggestive P value, including previously reported GJD2 (P=4.72 × 10−7 by linear regression using 2,991 individuals) for axial length and the novel genome-wide hit WNT7B for corneal curvature (Ptop=1.13 × 10−9 by linear regression using 2,747).

Back to article page