Figure 2: Assessment of interactive effect between WNT7B and GJD2 and association with the spherical equivalent. | Nature Communications

Figure 2: Assessment of interactive effect between WNT7B and GJD2 and association with the spherical equivalent.

From: Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

Figure 2

In Asian cohorts, the effects of GJD2 rs11073058 on the spherical equivalent were highest when the individual had the homozygous variant (AA genotype) at WNT7B rs10453441 (β=−0.54 D; 95% CI=−0.82 to −0.27 D), compared with individuals with the AG genotype (β=−0.24 D; 95% CI=−0.37 to −0.10 D; P=0.05 by z-test) or those with the GG genotype (β=−0.18 D; 95% CI=−0.32 to −0.05 D; P=0.02 by z-test). This trend was not observed in Caucasian cohorts.

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