Table 1 Results of the discovery stage.

From: Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia

 

Nearby genes

 

rs number

CHR

Position

n

Effect allele

β

Standard error

MAF

P value

Axial length

THSD7B

Not in gene

rs78534307

2

1,368,233,336

2,991

G

0.83

0.16

0.01

2.52 × 10−7

 

GJD2

In gene

rs11073058

15

34,697,425

2,991

T

0.17

0.03

0.46

4.72 × 10−7

Spherical equivalent

LOC101928675

Not in gene

rs6732520

2

228,821,808

2,730

C

−1.85

0.35

0.01

1.73 × 10−7

 

RPL6P27

Not in gene

rs4798444

18

6,455,641

2,730

A

0.36

0.07

0.50

2.86 × 10−7

Corneal curvature

WNT7B

In gene

rs200329677

22

45,973,898

2,747

C

0.047

0.0077

0.28

1.13 × 10−9

  1. CHR, chromosome.
  2. Regions with a P value (linear regression) less than 1.0 × 10−6 are shown.
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