Figure 2: Signatures of DNA damage associated with aged DNA. | Nature Communications

Figure 2: Signatures of DNA damage associated with aged DNA.

From: Eighteenth-century genomes show that mixed infections were common at time of peak tuberculosis in Europe

Figure 2

These data from body 28 are representative of all eighteenth-century samples. (a) The four panels show the average base frequencies at positions within individual reads (grey box) flanked by all calls from reads in neighbouring sequences. (b) Frequencies of specific base substitutions at specific positions near the 5′-end (left panel) and 3′-end (right panel) occurring within reads. C to T changes are indicated by a red line, and G to A changes by a blue line.

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