Figure 2: Phenome heat map created for C. neoformans TF mutant strains.
From: Systematic functional profiling of transcription factor networks in Cryptococcus neoformans
Phenotype scores are represented in distinct colours based on qualitative or semi-quantitative measurement of >2 independent TF mutant strains under indicated growth conditions (abbreviated in the right panel). Red and blue in the heat map represent reduction and enhancement, respectively. Phenotype strengths (strong, intermediate and weak) are distinguished in gradients of red or blue, as indicated in the right panel. Genes reported previously or genes whose names are reserved in FungiDB14 are denoted in black, whereas genes that we newly named in this study are denoted in red. Transcriptional levels for each TF under distinct conditions were retrieved from the RNA sequencing data, which were reported in the previous C. neoformans H99 genome paper4.
