Figure 1
New BCC association signals. Loci are (a) 2p24 MYCN, (b) 2q33 CASP8-ALS2CR12, (c) 8q21 ZFHX4 and (d) 10p14 GATA3 loci in the Icelandic sample. Data are based on association signals (expressed as −log10(P) derived by logistic regression) for variants identified by whole-genome sequencing and imputation. The index SNP at each locus is labelled. Other variants are plotted in colours according to their r2 values relative to the index SNP as indicated in the legend (a). Recombination rates, in cM/Mb and based on Icelandic data, are plotted as red lines. The lower panel sections shows the locations of RefSeq genes and the chromosomal position (hg18 Build 36). The regions shown are ±500 kb from the index SNP except for 10p14 GATA3, where the region is extended to −1 Mb to show the location of the GATA3 gene.
