Figure 3: Effects of mutations α1L300Vβ2L296V and α1G258V β2G254V on GABA sensitivity.
From: The desensitization gate of inhibitory Cys-loop receptors

GABA concentration–response curves for wild-type (wt) α1β2 (EC50=4.1±0.7 μM, nH=1.08±0.07, n=6), α1L300Vβ2L296V (EC50=7.3±0.9 μM, nH=0.91±0.02, n=5) and α1G258V β2G254V receptors (EC50=3.0±0.9 μM, nH=0.89±0.19, n=5). Error bars are s.d.