Table 1 Relationship between ATM-p expression and clinicopathological parameters.
From: ATM kinase sustains HER2 tumorigenicity in breast cancer
Factors | ATM-p | *P value | |
|---|---|---|---|
n 167 | Negative | Positive | |
N (%) | N (%) | ||
Tumour size | |||
T1 | 42 (43.8) | 54 (56.3) | 0.354 |
T2–T4 | 26 (36.6) | 45 (63.4) | |
Lymph node status | |||
Negative | 42 (46.7) | 48 (53.3) | 0.091 |
Positive | 26 (33.8) | 51 (66.2) | |
Grading | |||
G1 | 10 (83.3) | 2 (16.7) | 0.001 |
G2 | 37 (45.1) | 45 (54.9) | |
G3 | 21 (28.8) | 52 (71.2) | |
Estrogen | |||
Negative | 22 (28.9) | 54 (71.1) | 0.005 |
Positive | 46 (50.5) | 45 (49.5) | |
Progesterone | |||
Negative | 27 (32.1) | 57 (67.9) | 0.023 |
Positive | 41 (49.2) | 42 (50.6) | |
HER2 | |||
Negative | 40 (50.0) | 40 (50.0) | 0.019 |
Positive | 28 (32.2) | 59 (67.8) | |
Ki67 | |||
Low | 38 (58.5) | 27 (41.5) | <0.001 |
High | 30 (30.3) | 69 (69.7) | |