Figure 2: H3K9/K14 acetylation of genes controlled by Mbd2. | Nature Communications

Figure 2: H3K9/K14 acetylation of genes controlled by Mbd2.

From: A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells

Figure 2

(a) ChIP sequencing composite profile showing H3K9/K14ac or input DNA signal (as read coverage) for WT (blue) and Mbd2−/− (red) BMDCs for a selection of genes with significantly altered mRNA profiles. Signal is displayed from −3 kb to +3 kb surrounding each annotated transcription start site (TSS). (b) Genome screenshots representing H3K9/K14ac signal in WT (blue) and Mbd2−/− (red) BMDCs at selected gene loci (Ccl17, Cd40, Irf4 and Mrc1). RefSeq genes are in black.

Back to article page