Figure 8: Thermodynamic validation of protein switches.
From: Design of protein switches based on an ensemble model of allostery

DSC thermograms in the absence of maltose for (a) c4 and c4-3G at pH 7.2, and (b) c4 and c4-3hx at pH 8. The thermograms shown correspond to the BLA domain and are representative of three independent experiments.