Figure 3: FGF19 (30 μg) corrects hyperglycemia in T1D rats by reducing lipolysis and hepatic acetyl CoA content.
From: FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
(a) Hepatic glucose production. (b,c) Whole-body palmitate and glycerol turnover. (d) Hepatic acetyl CoA concentrations. (e) Liver pyruvate carboxylase activity. (f) Liver glycogen content. (g) Liver gluconeogenic protein concentrations. Data are representative of mean±s.e.m. of n=6 per group, with comparisons by analysis of variance with Bonferroni’s multiple comparisons test.
