Figure 6: FGF1 (10 μg) reverses hyperglycemia in type 1 diabetic rats by suppressing the HPA axis, thereby reducing lipolysis and hepatic glucose production.
From: FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis

(a) Hepatic glucose production. (b) Whole-body glycolysis. (c–d) Whole-body palmitate and glycerol turnover. (e) Liver acetyl CoA. (f) Hepatic glycogen content. (g) Liver gluconeogenic protein expression. Data are representative of mean±s.e.m. of n=6 per group, with comparisons by analysis of variance with Bonferroni’s multiple comparisons test.