Figure 1: Prdx4 expression in the developing spinal cord.

(a–c) In situ hybridization of transverse sections of embryonic chick spinal cords shows Prdx4 transcript distribution. (d–h) Confocal micrographs of mouse spinal cords show the distribution of Prdx4 protein (red.) Boxes in d and g are magnified in e and h. Prdx4 is expressed in progenitors (*) and in newly differentiating (arrowheads), and postmitotic motor neurons (arrow in e); however Prdx4 is downregulated in terminally differentiated motor neurons at the end of neurogenesis (arrow in h). Scale bars, 20 μm.