Figure 1: Regional plots of the three loci associated with gout arthritis.
From: Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese
(a) 9p24.2, (b) 11p15.5 and (c) 17q23.2. The −log10 P values are shown for the SNPs within the 200-kb region on either side of the marker SNPs. The index SNP is shown in purple, and the r2 values of the other SNPs are indicated by colour. The r2 values are established based on the 1,000 Genome CHB and JPT data (June 2010). The Pgwas was obtained from the GWAS stage (analysed with logistic regression) and is shown for the genotyped (circle) and imputed (cross) SNPs. The Pmeta was obtained from a meta-analysis combining all of the data sets, including the discovery and replication stages. The genes within the relevant regions are annotated and indicated with arrows.
