Table 2 Comparisons of the four genome-wide significant SNPs in the HU versus control group and gout versus HU group.

From: Genome-wide association analysis identifies three new risk loci for gout arthritis in Han Chinese

Chromosome

SNP

Position

A1

Freq. in the gout group

Freq. in the HU group

Freq. in the control group

HU versus controls

Gout versus HU

       

P

OR

P

OR

9

rs12236871

357,9117

G

0.367

0.398

0.411

0.250

0.95

4.39E-03

0.88

11

rs179785

273,8095

G

0.454

0.527

0.526

0.933

1.00

1.34E-10

0.75

17

rs11653176

56,802,151

T

0.411

0.461

0.469

0.456

0.97

4.95E-06

0.81

17

rs9905274

56,805,223

T

0.427

0.458

0.472

0.209

0.95

4.97E-03

0.88

  1. HU, hyperuricemia; SNP, single-nucleotide polymorphisms; OR, odds ratio;
  2. Position, based on hg18; A1, minor allele for the whole sample; OR, odds ratio; P, P-value. The gout group includes 2,951 gout cases from GWAS, REP1 and REP2 stages, the HU (hyperuricemia) group includes 1,644 hyperuricemia cases, and the control group 3,309 controls from REP1 and REP2 stages. The OR and P values are based on the logistic regression.
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