Table 3 Mendelian randomization estimate of effect of T2D on CHD risk for subgroup analyses of SNP physiologic clusters.

From: A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease

Cluster name

Effect size (95% CI)

P value

I2 (95% CI)

No cluster

1.13 (1.04–1.23)

3.4E−03

59.5 (32.0–75.9)

Beta-cell cluster

1.07 (1.01–1.14)

2.3E−02

0 (0–67.6)

  1. CHD, coronary heart disease; CI, confidence interval; MR, Mendelian randomization; SNP, single nucleotide polymorphism; T2D, type-2 diabetes.
  2. Each P value is for the MR analyses.
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