Table 1 Genes regulated by Ndd1 and the APC/CCdh1.

From: Degradation of Ndd1 by APC/CCdh1 generates a feed forward loop that times mitotic protein accumulation

Gene

Ndd1 targets

APC/CCdh1 substrates

Hcm1 targets41

 

Previously reported

Putative*

This study

  

NDD1

   

+

+

Clb2

+27

+

+

+11

 

Cdc20

 

+

+

+38

 

Clb1

+27

 

+

+11

 

Spo12

 

+

+

+61

 

Ace2

+39

+

+

62

 

Swi5

+27

+

+

62

 

Bud4

 

+

+

 

+

Rax2

 

+

+

  

Ase1

  

+

+63

 

Cdc5

+35

 

+

+38

+

Iqg1

  

+

+64

 

Nrm1

  

+

+20

 

YHP1

  

+

+20

 

Cin8

  

+49

+

Kip1

  

+65

+

Hsl1

  

+66

 

Pds1

  

+6

 

Rnh202

  

+

 

Cik1

  

?

+67

+

Fin1

  

?

+68

 

Hof1

  

+

42

 

FIR1

Not tested

+19

 

YBR138C

Not tested

+19

 

MPS1

Not tested

+19

+

TOS4

Not tested

+19

 

EST1

Not tested

+69

 

DBF4

Not tested

+9,70

 
  1. APC/CCdh1, anaphase-promoting complex/cyclosome.
  2. *Binding to promoter reported by Simon et al.37 and confirmed in this study.
  3. Novel genes we identify here as Ndd1 targets or excluded from being targets.
  4. Our unpublished results.