Figure 1: Photolipids for the optical control of TRPV1. | Nature Communications

Figure 1: Photolipids for the optical control of TRPV1.

From: Photoswitchable fatty acids enable optical control of TRPV1

Figure 1

(a) Chemical structures of arachidonic acid and FAAzo1–8. (b) Chemical structures of TRPV1 agonists capsaicin (CAP), arvanil, olvanil, N-arachidonoyl dopamine and anandamide alongside photoswitchable vanilloids, AzCA1–8. (c) Chemical synthesis of AzCA4. Isomerization between cis- and trans-AzCA4 could be induced by irradiation with λ=365 nm (trans to cis) and λ=460 nm (cis to trans), respectively.

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