Figure 1: Forest plots summarizing ORs from studies contributing to colorectal cancer meta-analysis identifying six loci reaching genome-wide significance.
From: Genome-wide association study of colorectal cancer identifies six new susceptibility loci
The P value from the Cochran’s Q test for heterogeneity (Phet) is presented by SNP. ** indicates a subset of the study ARCTIC; *** indicates colorectal polyps. The study specific ORs (blue rectangles) and 95% confidence intervals (CI; horizontal bars) are plotted for each SNP. The red diamonds represent the summary OR and 95% CI for the ‘Discovery’ series (N=18,299 cases/19,656 controls) and ‘Overall’. The ‘Replication’ series included the Asian 1 (N=2,098 cases/6,172 controls) and Asian 2 (N=2,627 cases/3,797 controls) consortia.
