Table 1 Most significant polymorphic positions (omnibus test) and imputed classical alleles associated with ankylosing spondylitis susceptibility (P-value<1 × 10−2000).

From: Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Position

rs

AA position

Classical allele

χ 2

DF

P -value

31,432,180

97

14,857

5

<10−3,221

31,432,180

rs1071652

14,841

3

<10−3,221

31,430,829

rs41558317

14,823

1

<10−3,221

31,432,179

rs1140412

14,823

2

<10−3,219

HLA-B*27

14,820

1

<10−3,221

31,432,506

70

14,812

3

<10−3,215

31,432,129

114

14,402

2

<10−3,128

31,432,130

rs709055

14,401

2

<10−3,128

31,432,131

rs1050628

14,389

1

<10−3,127

HLA-B*27:05

14,220

1

<10−3,090

31,430,834

rs3819282

13,798

1

<10−2,999

31,430,345

rs3819299

13,757

1

<10−2,990

31,430,346

rs3819299

13,757

1

<10−2,990

31,451,646

rs4463302

12,898

1

<10−2,803

31,432,485

77

12,871

2

<10−2,795

31,432,486

rs1131217

12,849

1

<10−2,793

31,377,108

rs2394967

11,613

1

<10−2,524

31,381,125

rs6905036

11,552

1

<10−2,511

31,432,208

rs41556113

10,929

1

<10−2,376

31,432,843

rs41553720

10,299

2

<10−2,237

31,432,515

67

9,741

4

<10−2,112

31,432,515

rs1071816

9,725

3

<10−2,110

31,518,387

rs2844510

9,525

1

<10−2,071

  1. AA, amino acid; DF, degrees of freedom.