Table 2 Evidence for association of HLA-B alleles with susceptibility to ankylosing spondylitis. Effect sizes and levels of significance were estimated in stepwise conditional procedure, where for rounds 2 and onwards the test conditioned on the previous alleles.

From: Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

Round

HLA-B allele

OR (95% CI)

P -value

1

27:05

62.41 (56.90–68.45)

<10−321

2

27:02

43.41 (29.80–63.23)

1.07 × 10−122

3

07:02

0.82 (0.74–0.91)

5.04 × 10−6

4

57:01

0.75 (0.61–0.92)

5.13 × 10−4

5

51:01

1.33 (1.14–1.56)

2.14 × 10−3

6

47:01

2.35 (1.43–3.86)

2.25 × 10−3

7

40:02

1.59 (1.19–2.14)

4.65 × 10−3

8

13:02

1.43 (1.14–1.80)

4.29 × 10−3

9

40:01

1.22 (1.06–1.40)

4.93 × 10−3

All other alleles

>0.05

  1. CI, confidence interval; OR, odds ratio;
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