Figure 2: Axonal tracts are defective in MAP6-KO mice. | Nature Communications

Figure 2: Axonal tracts are defective in MAP6-KO mice.

From: Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth

Figure 2

(a) Representative galleries of FA colour maps in which the colour code indicates the spatial direction of the free diffusion along the axons with medial-lateral (red), ventral-dorsal (blue) and rostral-caudal (green) orientations. Scale bar, 1 mm. (b) Representative FA colour-maps (slices 6 from a) used to draw each axonal tract. FA values and region of interest (ROI) surface areas for each tract are reported in Table 1. Scale bar, 500 μm. (c) Representative coronal brain sections of WT and MAP6-KO forebrain stained with gold chloride and counterstained with cresyl violet used to measure the area and the thickness of axonal tracts and brain regions. Scale bar, 500 μm. Note in panels b′ and d′ that the post-commissural part of fornix (arrow, pf) is undetectable in the MAP6-KO brain slice after gold staining or DTI images. cc=corpus callosum; cg=cingulum; Ctx=cortex; df=dorsal fornix; mt=mammillary tract and pf=post-commissural fornix.

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