Figure 1: Significance of zinc finger protein 304 expression in human ovarian carcinoma (OC).
From: The ZNF304-integrin axis protects against anoikis in cancer
(a) Graphical representation of computational analysis using The Cancer Genome Atlas (TCGA) high-grade serous OC data set. (b) The probability of survival in OC patients analysed in the training set (two-third of cases; P<0.05, Log-rank test) and (c) in the validation set (one-third of cases; P<0.05, Log-rank test). Kaplan–Meier curves indicate that high ZNF304 expression is a predictor of poor overall survival in patients with OC (n=88, P=0.03, Log-rank test). (d) Western blot analysis of ZNF304 protein expression and (e) RT-PCR analysis of ZNF304 mRNA in six ovarian cancer cell lines and one non-transformed ovarian cell line (HIO180).
