Figure 7: A schematic representation of mechanisms by which ZNF304 downregulation enhances anoikis in tumour cells.
From: The ZNF304-integrin axis protects against anoikis in cancer
The model illustrates that silencing ZNF304 leads to anoikis in tumour cells, whereas high-ZNF304-expressing cells gain resistance to anoikis through increased integrin β1 expression and activation of focal adhesion complex members.
