Table 1 T-Red phenotype is autosomal recessive.

From: KDEL receptor 1 regulates T-cell homeostasis via PP1 that is a key phosphatase for ISR

Parents

Generation

n

Memory phenotype

%

G3.mutant × G3.mutant

G4

28

28

100

B6 × G3.mutant

F1

21

0

0

 

F2

106

21

19.8

  1. T-cell phenotypes in a mutant mouse strain were inherited as a simple autosomal recessive trait in the progeny. Peripheral blood of mice between 6 and 12 weeks old was examined for CD44 levels of CD8 T cells.