Figure 7: PACS-2 regulates intestinal tissue homeostasis.

(a) Histology of the small intestine of Pacs2^−/− mice. Scale bars, 63 μm. (b) The ratio of villus height to crypt depth in jejunum and ileum was quantified using four control and four Pacs2^−/− mice. More than 100 villi were assessed for each genotype and segment. Graphs show mean values±s.e.m. Data were analysed by unpaired two-tailed Student’s t-test. ***P<0.001.