Figure 4: Mutant and WT GARS and YARS proteins display similar subcellular localization in motor and sensory neurons. | Nature Communications

Figure 4: Mutant and WT GARS and YARS proteins display similar subcellular localization in motor and sensory neurons.

From: Impaired protein translation in Drosophila models for Charcot–Marie–Tooth neuropathy caused by mutant tRNA synthetases

Figure 4

(a–h) GARS immunostaining reveals the subcellular localization of GARS proteins at third instar larval NMJs (a–d) and motor neuron cell bodies (e–h) upon expression in motor neurons (OK371-GAL4). (i–t) Subcellular localization of YARS proteins at third instar larval NMJs (i–l; nsyb-GAL4), motor neuron cell bodies (m–p; nsyb-GAL4) and class IV multidendritic sensory neurons (q–t; ppk-GAL4), as revealed by YARS immunostaining. Scale bars, 20 μm (a–p) and 100 μm (q–t).

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