Figure 6: Potential halogen bonds involving p-iodo-phenylalanine.
From: Supramolecular amplification of amyloid self-assembly by iodination
IR and Raman spectroscopies are more consistent with the occurrence of type a interaction, however, other interactions reported cannot be discounted. (a) Orthogonal hydrogen and halogen bonds involving the carbonyl oxygen atom of the peptide bond36. (b) Type II iodine···iodine contacts23. (c) Iodine···π interactions49. (d) Triangular iodine synthon50.
