Figure 4: Selected difference surfaces between equilibrium probability densities of CBD–Apo and CBD–cAMP.
From: Allostery through the computational microscope: cAMP activation of a canonical signalling domain
(a) The difference surface for 10% or more density for the N3A Motif of CBD–Apo over CDB–cAMP. Arrows indicate interface between PKA’s catalytic and regulatory subunits (b) The different surface for 1% or more density for the B/C Helix of CBD–Apo over CDB–cAMP.
