Figure 5: Surface representation of HLA proteins and their sub-pockets.

(a) HLA-B*38:02. The pocket positions are defined on the basis of the crystal structures of peptide-HLA-B*15:01 complex. The sub-pockets of HLA-B*38:01 are located at similar positions. (b) HLA-DRA/DRB1*08:03. The pocket positions are defined on the basis of the crystal structure of peptide-HLA-DR1 complex.