Figure 2: Pirt and P2X3 are co-expressed in bladder nerve fibres.
From: Pirt reduces bladder overactivity by inhibiting purinergic receptor P2X3
(a–l) The expression of Pirt and P2X3 in bladders. (a–c) Tuj-1-ir (green) and Pirt-ir (red) in the mouse bladder. (d–f) SMA-ir (green) and Pirt-ir (red) in the mouse bladder. (g–l) Tuj-1-ir (green) or SMA-ir (green) and P2X3-ir (red) in the mouse bladder. The corresponding merged images are on the right. Scale bar, 100 μm. (m–r) The co-expression of Pirt and P2X3. WT, WT mouse. Pirt−/−, Pirt-knockout mouse. Pirt-ir, green; P2X3-ir, red. The merged images are from the left-side images. Scale bar, 100 μm.
